RAB31 (Ras-related protein in brain 31)
نویسندگان
چکیده
منابع مشابه
Monoterpene regulation of Ras and Ras-related protein expression.
Monoterpenes, derived primarily from plants, are products of the isoprenoid biosynthetic pathway and function as chemical messengers with diverse functions. The biochemical bases for these activities are largely undefined. The Ras small GTPase superfamily of proteins consists of isoprenylated proteins that play key roles in signal transduction pathways known to regulate diverse cellular functio...
متن کاملPurification of ras GTPase activating protein from bovine brain.
In cytosolic extracts of bovine brain, we detected ras GTPase activating protein (GAP) activity that stimulated the GTP hydrolytic activity of normal c-Ha-ras p21 but not that of the oncogenic [Val12]p21 variant. GAP was purified 19,500-fold by a five-column procedure involving DEAE-Sephacel, Sepharose 6B, orange dye and green dye matrices, and Mono Q resins. A single major protein band of 125 ...
متن کاملp21 ras-related protein levels depend on sample handling.
Proteins immunologically related to oncogene products are detectable in plasma, serum, and urine. We and others are studying the relationship between cancer risk and circulating proteins immunologically related to the ras (1-6), c-erbB2 (7), c-myc (8), mt-i (9), and other (10) oncogene products. We recently observed that p21 rasrelated plasma protein levels depend on initial sample processing m...
متن کاملThe Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation.
Presently, nothing is known about the function of the Ras-related protein Rheb. Since Rheb shares significant sequence identity with the core effector domains of Ras and KRev-1/Rap1A, it may share functional similarities with these two structurally related, yet functionally distinct, small GTPases. Furthermore, since like Ras, Rheb terminates with a COOH terminus that is likely to signal for fa...
متن کاملDexamethasone-induced Ras-related protein 1 is a potential regulatory protein in B lymphocytes.
Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein of the Ras family which probably has a regulatory function. We demonstrate that Rasd1 mRNA is expressed in mouse lymph node cells in response to inhibitory stimuli. Rasd1 mRNA is present at very low levels in freshly isolated cells, but it is rapidly up-regulated in culture and is expressed at elevated levels in cells whose prolif...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2018
ISSN: 1768-3262
DOI: 10.4267/2042/66072